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Principles of Biochemistry (Loose Leaf) (6th) Edition 1429293128 9781429293129
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Problem 1P
Chapter
CH1
  • CH1
  • CH2
  • CH3
  • CH4
  • CH5
  • CH6
  • CH7
  • CH8
  • CH9
  • CH10
  • CH11
  • CH12
  • CH13
  • CH14
  • CH15
  • CH16
  • CH17
  • CH18
  • CH19
  • CH20
  • CH21
  • CH22
  • CH23
  • CH24
  • CH25
  • CH26
  • CH27
  • CH28
Problem
1P
  • 1P
  • 2P
  • 3P
  • 4P
  • 5P
  • 6P
  • 7P
  • 8P
  • 9P
  • 10P
  • 11P
  • 12P
  • 13P
  • 14P
  • 15P
  • 16DAP
Step-by-step solution
Step 1 of 8

(a) According to the given data:

The typical eukaryotic cell has a cellular diameter = 50 µm.

An electron microscope is used to magnify a cell of = 10,000 fold.

The diameter of the magnified cell is = 50 µm.

Electron microscope is used to magnify a cell to 10,000 fold = 104 µm.

The magnified cell can be calculated by the following equation:

Step 2 of 8

(b) According to the given data:

The diameter of the actin molecule = 3.6 nm (D = r/2).

The radius of a globular actin molecule is =

The volume of the sphere is calculated by the following equation:

Where,

r =

= 3.14.

The volume of one actin molecule (in cu.mm) is given by:

Step 3 of 8

Hence, the volume of one actin molecule is.

Step 4 of 8

The cell volume can be calculated as follows:

…… (1)

Where,

Substitute the values in equation (1)

The number of actin molecules accommodated inside the cell is calculated as follows:

= 2.66 x 1012 or 2.7 x 1012 molecules.

Step 5 of 8

(c) According to the given data:

The diameter of the mitochondrion is given by =

The radius of the mitochondria is given by =.

The shape of the mitochondria is spherical.

Therefore the volume of a spherical mitochondrion is calculated by the equation:

= 4/3pr3

Where,

Step 6 of 8
r = = 0.75 µm.

= 3.14.

=

= 1.77 x 10-.

The value obtained from volume of the actin molecule is found to be:

Therefore, the number of mitochondria that is present in the liver cell is 3600 mitochondria.

Step 7 of 8

(d) The volume of the eukaryotic cell is = 6.5 x 10-14 m3 (or)

The volume of the eukaryotic cell is = 6.5 x 10-8 cm3 or 6.5 x 10-8 ml.

Avogadro number = 6.02 x 1023molecules/mol.

One Liter of 1 mM solution consists of:

The number of glucose molecules is calculated by: Multiplying the concentration of glucose and the product of the cell volume.

Therefore, the number of glucose molecules present in eukaryotic cell is

Step 8 of 8

(e) The enzyme hexokinase catalyzes the metabolism of glucose in the first step, during the conversion of glucose into glucose-6-Phosphate.

According to the given data:

The concentration of glucose is given by = 20 µm.

The concentration of glucose/hexokinase is:

Thus, 50 molecules of glucose are available as substrate in hexokinase.

Corresponding textbook


Principles of Biochemistry (Loose Leaf) | 6th Edition
Principles of Biochemistry (Loose Leaf) | 6th Edition
ISBN-13:9781429293129ISBN:1429293128Authors:David L Nelson,Michael M Cox Rent | Buy
Principles of Biochemistry (Loose Leaf) (6th Edition) Edit edition…
Chapter 1, Problem 1P is solved.
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